It’s March of 2019, and twenty-eight-year-old Jules Gold—anxious, artistically frustrated, and internet-obsessed—has been living alone in the apartment she once shared with the man she thought she’d marry when her younger sister Poppy comes to crash. Indefinitely. Poppy, a year and a half out from a suicide attempt only Jules knows about, searches for work and meaning in Brooklyn while Jules spends her days hate-scrolling the feeds of Mormon mommy bloggers and waiting for life to happen.

Then the hives that’ve plagued Poppy since childhood flare up. Jules’s uterus turns against her. Poppy brings home a maladjusted rescue dog named Amy Klobuchar. The girls’ mother, a newly devout Messianic Jew, starts falling for the same deep-state conspiracy theories as Jules’s online mommies. Jules, halfheartedly struggling to scrape her way to the source of her ennui, slowly and cruelly comes to blame Poppy for her own insufficiencies as a friend, a writer, and a sister. And Amy Klobuchar might have rabies. As the year shambles on and a new decade looms near, a disastrous trip home to Florida forces Jules and Poppy—comrades, competitors, constant fixtures in each other’s lives—to ask themselves what they want their futures to look like, and whether they’ll spend them together or apart.