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COSRX took the PDRN trend that REJURAN popularized and built it into a daily toner format. This 5 PDRN B5 Vital Soothing Toner pairs PDRN (polydeoxyribonucleotide, the salmon-DNA-derived skin regenerator) with panthenol (vitamin B5, the ceramide-adjacent barrier soother). The combination is smart: PDRN drives regeneration signaling, B5 supports barrier calming. Together they give a daily-use toner that actually does work beyond hydration.
At $51 for 280ml, this is higher-priced than COSRX's classic toners but lower than REJURAN's PDRN-focused line. It positions the PDRN category for users who want to try the ingredient daily without committing to REJURAN pricing.
PDRN supports skin cell regeneration signaling and collagen production. Panthenol provides immediate barrier soothing and hydration. The combination works well on stressed, irritated, or post-procedure skin. Lightweight toner format layers under anything in the routine.
After cleansing, press 3 to 4 drops into skin. Use AM and PM. Follow with serum and cream. Can be layered generously for a "hydration layering" routine.
Different formulation intensities. REJURAN uses the c-PDRN technology developed for their injection line. COSRX uses a different PDRN form at 5% inclusion. REJURAN is the clinical benchmark; COSRX is the accessible daily-use version.
Immediate calming and hydration. Regeneration benefits build over 4 to 8 weeks.
No. PDRN is salmon-derived.
Yes. Use as the first hydration layer, then follow with retinol or vitamin C as tolerated.
Yes, the B5 soothing anchor makes it well-tolerated.
Pair with COSRX Hyaluronic Acid Hydra Power Essence for layered hydration. Browse the full COSRX collection or Korean toners.
Ships within 48 hours · Estimated delivery Jul 6 - Jul 11
US$40
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