It requires a 30 gallon or larger aquarium with plenty of loose coral rubble, ample swimming room, and a sand bottom for burrowing. It rarely becomes aggressive towards other fish, but it is territorial, and will fight with its own kind unless they are a mated pair. It may try to jump out of the aquarium or other small openings, therefore, a tight-fitting lid is required to prevent escape.

The Yellow Prawn Goby diet should include a variety of mysis shrimp, brine shrimp, table shrimp, and frozen preparations for carnivores. It should be fed at least twice per day.