Miskatonic University The Restricted Collection is a card game set in the world of Call of Cthulhu, created by world-renowned game designer Reiner Knizia. It takes place in the treacherous and terrifying Restricted Collection of Miskatonic University's Orne Library. It includes grimoires, elder signs, academic politics and madness, and that endlessly renewable resource: graduate students!

In Miskatonic University: The Restricted Collection, you all compete with each other for the prestigious position of head of the library committee. Tonight you will gather in Dr.'s office. Armitage, where he will decide who will get the coveted position. But just as the meeting is about to start, you hear blood-curdling screams...

The game is a quest. An extremely dangerous quest. Dr. Henry Armitage, Chief Librarian, wants you to search the dangerous Restricted Collection for fragments of grimoire lore and recover pieces of a certain sigil to help him defeat the horror that has invaded the university.

You explore the Restricted Collection. However, it is a dangerous journey and you must be prepared to flee before you go crazy! The winner is the professor who finds the most sets while maintaining some semblance of sanity. Also be on the lookout for hapless wandering graduate students, as they can help with defense!