BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively.

Product information

CAS Number: 2444837-63-0

Molecular Weight: 610.93

Formula: C25H25ClF6N4O5

Chemical Name: 5-chloro-7-[(4-ethylpiperazin-1-yl)(pyridin-3-yl)methyl]quinolin-8-ol; bis(trifluoroacetic acid)

Smiles: CCN1CCN(CC1)C(C1=CC(Cl)=C2C=CC=NC2=C1O)C1C=NC=CC=1.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F

InChiKey: LTJCVYFLZPEFLV-UHFFFAOYSA-N

InChi: InChI=1S/C21H23ClN4O.2C2HF3O2/c1-2-25-9-11-26(12-10-25)20(15-5-3-7-23-14-15)17-13-18(22)16-6-4-8-24-19(16)21(17)27;2*3-2(4,5)1(6)7/h3-8,13-14,20,27H,2,9-12H2,1H3;2*(H,6,7)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (204.61 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.