Autotaxin Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22261-50, RA22261-100 Citations, Manuals and MSDS Available upon request. Background: ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) Homo sapiens The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: ENPP2; ATX; PDNP2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; E-NPP 2; Autotaxin; Extracellular lysophospholipase D; LysoPLD Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 5168 Protein MW (KDa): 98 SWISS: Q13822 Source: Rabbit Research Use Only