Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer.

Product information

CAS Number: 1443547-43-0

Molecular Weight: 2330.63

Formula: C132H96N12O18S6

Chemical Name: 4-[7,12-diphenyl-17-(4-sulfophenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,11(23),12,14,16,18(21),19-decaen-2-yl]benzene-1-sulfonic acid; 4-[7,12-diphenyl-17-(4-sulfophenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21)-decaen-2-yl]benzene-1-sulfonic acid; 4-[7,12-diphenyl-17-(4-sulfophenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,9,11(23),12,16,18(21),19-decaen-2-yl]benzene-1-sulfonic acid

Smiles: OS(=O)(=O)C1C=CC(=CC=1)C1C2=CC=C(N2)C(=C2C=CC(=N2)C(=C2C=CC(N2)=C(C2C=CC(=CC=2)S(O)(=O)=O)C2CCC=1N=2)C1C=CC=CC=1)C1C=CC=CC=1.OS(=O)(=O)C1C=CC(=CC=1)C1C2=CC=C(N2)C(C2C=CC=CC=2)=C2CCC(=N2)C(=C2C=CC(N2)=C(C2C=CC=1N=2)C1C=CC(=CC=1)S(O)(=O)=O)C1C=CC=CC=1.OS(=O)(=O)C1C=CC(=CC=1)C1C2=CC=C(N2)C(=C2C=CC(=N2)C(C2C=CC=CC=2)=C2CCC(N2)=C(C2C=CC=1N=2)C1C=CC(=CC=1)S(O)(=O)=O)C1C=CC=CC=1

InChiKey: AINQERPKMNDVQT-KHRRKNAZSA-N

InChi: InChI=1S/3C44H32N4O6S2/c3*49-55(50,51)31-15-11-29(12-16-31)43-37-23-21-35(46-37)41(27-7-3-1-4-8-27)33-19-20-34(45-33)42(28-9-5-2-6-10-28)36-22-24-38(47-36)44(40-26-25-39(43)48-40)30-13-17-32(18-14-30)56(52,53)54/h1-18,21-26,46-47H,19-20H2,(H,49,50,51)(H,52,53,54);1-21,23,25-26,46-47H,22,24H2,(H,49,50,51)(H,52,53,54);1-24,46-47H,25-26H2,(H,49,50,51)(H,52,53,54)/b41-33-,41-35-,42-34-,42-36-,43-37-,43-39-,44-38-,44-40-;41-33-,42-36-,43-39-,44-38-;41-33-,41-35-,42-34-,42-36-,43-37-,43-39-,44-38-,44-40-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The endosomal/lysosomal localizing photosensitizer Fimaporfin (0.35 μg/ml) is used in the drug delivery technology photochemical internalization (PCI) in combination with drugs that usually are trapped in endosomes and/or lysosomes.

Products are for research use only. Not for human use.