PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively .

Product information

CAS Number: 77422-99-2

Molecular Weight: 362.34

Formula: C19H14N4O4

Chemical Name: 7-benzamido-4-methyl-9-oxo-4H,9H-pyrazolo[3,2-b]quinazoline-2-carboxylic acid

Smiles: CN1C2=CC(=NN2C(=O)C2=CC(=CC=C12)NC(=O)C1C=CC=CC=1)C(O)=O

InChiKey: IAZAGXDMMVWYKF-UHFFFAOYSA-N

InChi: InChI=1S/C19H14N4O4/c1-22-15-8-7-12(20-17(24)11-5-3-2-4-6-11)9-13(15)18(25)23-16(22)10-14(21-23)19(26)27/h2-10H,1H3,(H,20,24)(H,26,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 36 mg/mL (99.35 mM; Need ultrasonic and warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.