KCNE1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10025-50, ES10025-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily E regulatory subunit 1 (KCNE1) Homo sapiens The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 14kD

Human Gene ID: 3753

Human SWISS Prot NO: P15382

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Apical cell membrane. Membrane raft. Colocalizes with KCNB1 at the plasma membrane (By similarity). Targets to the membrane raft when associated with KCNQ1 (PubMed:20533308).

Research Use Only