Histone H2A.Z (Acetyl Lys7) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20532-50, ES20532-100

Citations, Manuals and MSDS Available upon request.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Alternate Name: H2AFZ; H2AZ; Histone H2A.Z; H2A/z

Source: Rabbit

Applications: WB

Dilution: WB: 1:500-1000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 14kD

Human Gene ID: 3015

Human SWISS Prot NO: P0C0S5

Subcellular Location: Nucleus. Chromosome.

Research Use Only