ASC-1 (G105) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2072-50, BS2072-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15650

Host: Rabbit

Reactivity: Human, Mouse

Applications: IHC, IF

All Applications: IHC: 1:50~1:200
IF: 1:50~1:200

Background: Activating signal cointegrator 1 (ASC1) is a novel 66 kDa coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ASC-1 (G105) polyclonal antibody detects endogenous levels of ASC-1 protein.

Bioworld Molecular Weight: ~ 66 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of ASC-1 (G105) pAb in paraffin-embedded human colon carcinoma tissue at 1:5000. cytoplasmic and nucleus staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase., Immunohistochemistry (IHC) analyzes of ASC-1 (G105) pAb in paraffin-embedded human esophagus carcinoma tissue at 1:5000. cytoplasmic and nucleus staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Alternative Name: Activating signal cointegrator 1; ASC1; Thyroid receptor-interacting protein 4; TR-interacting protein 4; TRIP-4; TRIP4

Immunogen: Synthetic peptide, corresponding to amino acids 72-124 of Human ASC-1.

Conjugate: Unconjugated

Modification: Unmodified