CUN79177, also known as BRM/BRG1 ATP Inhibitor-1, is an orally Active Inhibitors (IC50=5 nM) of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. CUN79177 was first reported ion Journal of Medicinal Chemistry (2018), 61(22), 10155-10172.

Product information

CAS Number: 2270879-17-7

Molecular Weight: 318.27

Formula: C11H9F3N4O2S

Chemical Name: 3-[3-(difluoromethyl)-1,2-thiazol-5-yl]-1-[2-fluoro-5-(hydroxymethyl)pyridin-4-yl]urea

Smiles: OCC1=CN=C(F)C=C1NC(=O)NC1=CC(=NS1)C(F)F

InChiKey: CKYCAIAVJIFWPE-UHFFFAOYSA-N

InChi: InChI=1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.