Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23459-50, RA23459-100 Citations, Manuals and MSDS Available upon request. Background: caspase 2 (CASP2) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 835 Protein MW (KDa): 22 SWISS: P42575 Source: Rabbit Research Use Only