Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2353410-11-2

Molecular Weight: 481.54

Formula: C19H39N5O9

Chemical Name: 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosane-27-hydrazide

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NN

InChiKey: XSHZSHNFUKYUOV-UHFFFAOYSA-N

InChi: InChI=1S/C19H39N5O9/c20-23-19(25)1-3-26-5-7-28-9-11-30-13-15-32-17-18-33-16-14-31-12-10-29-8-6-27-4-2-22-24-21/h1-18,20H2,(H,23,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.