Integrin α3 (CD49c) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0243P-50, NCP0243P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P26006

Host: Rabbit

Reactivity: Human

Applications: WB, IF

All Applications: WB: 1:1000~1:2000
IF 1:50~1:200

Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Integrin α3 (CD49c) polyclonal antibody detects endogenous levels of Integrin α3 (CD49c) protein.

Bioworld Molecular Weight: ~ 116 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Integrin α3 (CD49c) polyclonal antibody at 1:1000 dilution
Lane 1: EC9706 whole cell lysate (30ug)
Lane 2: A549 whole cell lysate (30ug), Immunofluorescence analysis of A549 cells using Integrin α3 (CD49c) pAb at dilution of 1:200.

Alternative Name: Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD_antigen: CD49c; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; ITGA3; MSK18

Immunogen: Recombinant protein of human Integrin α3 (CD49c).

Conjugate: Unconjugated

Modification: Unmodified