Recombinant Mouse Semaphorin-4C/SEMA4C Protein (Fc Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSM041138-10, PKSM041138-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Semaphorin-4C; SEMA4C

Target Synonym: Semaphorin-4C; Semaphorin I; S4c; Semacl1; Semai; Sema I; Semaphorin-C-like 1; M-Sema F; Sema4c

UNIProt ID: Q64151

Target Species: Mouse

Expression Host: HEK293 Cells

Fusion Tag: C-Fc

Accession: Q64151

Background: Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Sequence: Ala21-Gly664

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 99.3 kDa

Observed MW: 120 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only