APPL1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22001-50, RA22001-100

Citations, Manuals and MSDS Available upon request.

Background: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1) Homo sapiens The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: APPL1; APPL; DIP13A; KIAA1428; DCC-interacting protein 13-alpha; Dip13-alpha; Adapter protein containing PH domain; PTB domain and leucine zipper motif 1

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 26060

Protein MW (KDa): 80

SWISS: Q9UKG1

Source: Rabbit

Research Use Only