TGFβ1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20507-50, RA20507-100

Citations, Manuals and MSDS Available upon request.

Background: transforming growth factor beta 1 (TGFB1) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB: 1:1000-2000 IHC: 1:200-500

Alternative Names: TGFB1; TGFB; Transforming growth factor beta-1; TGF-beta-1

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7040

Protein MW (KDa): 12,25,45-65

SWISS: P01137

Source: Rabbit

Research Use Only