CAC1A rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11416-50, ES11416-100

Citations, Manuals and MSDS Available upon request.

Background: calcium voltage-gated channel subunit alpha1 A (CACNA1A) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human protein . at AA range: 1401-1450

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 275kD

Human Gene ID: 773

Human SWISS Prot NO: O00555

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only