Prealbumin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91105-50, BS91105-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P02766(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP,

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200

Background: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Prealbumin polyclonal antibody detects endogenous levels of Prealbumin protein.

Bioworld Molecular Weight: 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Prealbumin on human lung lysates using anti-Prealbumin antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Prealbumin antibody. Counter stained with hematoxylin.

Alternative Name: TTR, Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, Epididymis luminal protein 111, HEL111, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Prealbumin Thyroxine-binding, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY, TTR, TTR protein,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified